@Cath62 your up early. I found when I was taking it in the morning I would have a lot of joint pain and difficulty moving for the day. By taking it at night I figure I'm asleep well mostly asleep so hopefully not too impeeding on the next day. I am so slow when I walk I cant walk fast enough for any cardio for exercise or weight loss. If you were to see me move you would assume I'm 25 years older than I am.I'm currently having leg pain, foot and heel pain, I still have some neuropathy in my toes. My legs are twitching. Once my sleep apnoea is sorted my dr is going to investigate restless leg syndrome. Sometimes I wonder when will it ever end.But then I remember all I have overcome and I am happy to be here so I shuffle forward.