Forum Discussion

Amazonian's avatar
Amazonian
Member
7 years ago

Horrid Bone and Joint Pain after Pegfilgrastim (Neulasta) injection????

Just wondering if anyone has had the horrible side effects of severe joint/bone pain from the waist down after their shot of the white blood cell booster Pegfilgrastim? 
My oncologist said it could be handled with panadol, well a trip to the ER because it was unbearable has left me having 5mg endone every four hours, but this ain’t working. I feel horrible already from the normal chemo side effects (TC, first dose) and to have this on top, plus adding more drugs to my body is starting to really stress me out. 
I cannot seem to find any info on Australian reputable sites about side effects and treatments of for the Pegfilgrastim. So I’m willing to hear any advise to get me through this crappy time !! 
medication
side-effects
  • Blossom1961's avatar
    Blossom1961
    Member
    7 years ago
    Peg gave me horrendous pain over my whole torso area. I felt as if all the bones were severely bruised. My back was the worst. Hubby couldn’t even cuddle me.
  • Zoffiel's avatar
    Zoffiel
    Member
    7 years ago
    I loathed that drug @Amazonian I've had chemo twice and found that Loratadine (Claratyne) made the world of difference. Ask your onc, but I have never heard of anyone being told they can't take it and it is standard practice in some places. Start the day before chemo and take one a day for 7 days. Some oncologists poo poo the idea, but there have been studies in the UK that suggest it is helpful. At $1 a day it's worth a go.
    The theory is that the antihistamine helps with the bone oedema caused by the Peg injection. Some people have a worse time with that than others and there is no way I could cope with just Panadol. Mxx
  • primek's avatar
    primek
    Member
    7 years ago
    Yes it is common and I needed pain killers for a day or so after (mine was my neck and back)  However Clarityne, an antihistamine has been reported on here as assisting with dramatically reducing that pain. I haven't tried it but a number of women have and state it really helped.
    Some chemo also causes pain. I was on taxol weekly and got terrible leg pains around day 3....I didn't have Pegfilgrastim during that part of chemo so I know it wasn't that causing it. I didn't have the pain initial round but it got worse each round.