I just wanted to add, I took Tamoxifen for 4yrs until I had a recurrence and I had no side effects, maybe some mild stiffness but nothing like side effects on other Ai's such as Arimidex and Aromasin, they are definitely much more difficult and I attribute that to purely being thrown into an unnatural menopause. So combination of that plus my Aromasin now which only side effects is stiffness and pain. Magnesium makes a massive difference for me. I honestly believe the depression is attributed to the entire thing, it's massive but in the last 6 years on these its definitely not medication. xx