Menopause itself caused me depression problems and I eventually adjusted. I can imagine tamoxifen is similar if not through Menopause. However we are all prone to down days through and after treatment. It's when it continues for a while it is depression and sometimes just talking to a counsellor, taking up exercise and focussing on a nourishing balanced diet is enough to bring you through it. We will all grieve a bit for our old life, and that's perfectly normal. Allow the feelings, have a flat day or two, then pick yourself up and on we go. If however you get stuck in that constant sad mindset then seek help. Kath x