Kisqali/ Letrozel exhaustion

Keep sn eye on tbe BP and let your treating team know about this dide effects. I was having heart issues which resulted in my BP plummeting. It resolved with help. Kath x

Hi @MeganM, I've been on the same combination as you for the last 13 months, most days I'm OK, but once a month or so, I get a couple of days where I just need to rest up completely, your bp was pretty low though, I'd mention that to your onc next time you see him/ her. This combination is quite easy on me at least, I have found that taking it after my evening meal seems to work best. Maybe ease back into exercise a bit more slowly.

Thanks @Wendy55 and @Zoffiel For your sound advice which I’ve mostly taken.

My McGrath Nurse said that it’s probably an accumulative effect of the drugs as the tiredness as been for most of the 3rd cycle. I’m going to revert to taking the Kisqali at night to see if this gives me more energy and go easier on the exercise. 

Hi @MeganM,
You certainly took a lot on yesterday! gym and going back to work! as @zoffiel said anything unusual let your doctor know, although a good guess would be just organized for work and going to the gym would have tired you out, I do know that the combination you are on does cause fatigue, however we all respond differently to the drugs we are on, there are several ladies in the metastatic group who are on the same drugs as you, perhaps they might read this and put up a post about how they are going,try not to put too much on yourself,going to work full time and doing metastatic breast cancer is a hard enough gig as it is!
wendy55

Letting your doctor know about anything that is unusual for you is always a good idea. Hang in there, this shit is exhausting.