Hello allVery long time since I’ve poked my head into this discussion forum. I’d like to hear what other younger pre-menopausal patients around the country are being recommend regarding duration of total endocrine therapy. I myself am now onto year 6 of ovarian suppression and AI, a choice I have continued although I could have switched to tamoxifen alone. Please comment with your doctors advice and your stage/diagnosis. Are you doing:5 years ovarian suppression and aromatase inhibitor 7 years ovarian suppression and aromatase inhibitor 10 years ovarian suppression and aromatase inhibitor 5 years tamoxifen +/- ovarian suppression and then further 5 years ovarian suppression and aromatase inhibitor 10 years tamoxifen alone

Grade 2B, Stage 2, 10 years AI (letrozole) and (at least) 5 years ovarian suppression

Hi @youngdogmum I was 47 (premenopausal) and diagnosed with stage 2 triple positive. I had neoadjuvant chemo which put me into chemical menopause, with pCR at surgery. I have been on Tamoxifen since July and will continue for two years (to confirm I stay in menopause) and may then switch to an AI for a minimum of three years.I haven't yet discussed anything further than 5 years with my oncologist.

cactusk said: Grade 2B, Stage 2, 10 years AI (letrozole) and (at least) 5 years ovarian suppression @cactusk can I askwhy 10 years of AI for you when the studies say 5 for most? (I am genuinely interested to hear the recommendation from your onc)what Is your plan for ovarian suppression beyond the 5 years? An oopherectomy?

Hi there,I was peri-menopausal when I was diagnosed. My onc has said that although 5 years is standard at present, studies will come through within the next 5 years that make it more likely that I'll be on the AI's for at least 7, but more likely 10 years. For the ovarian suppression, I was surprised that I would need to be on this for more than 2 - 3 years, given i was near to (but not quite) menopausal, hence my understanding that at least 3-5 years for the Zoladex, and that could be extended. I'm not sure what tests would need to happen for this to cease. I can choose an oophorectomy at any stage to cease the monthly injections, but I'm not keen for another procedure just yet.Have you discussed Ribociclib with your onc too? i'm also on Zometa (as 6 monthly infusions) and I"m not sure how long that will go on for - i assume as long as the AI's do.K

Duration of endocrine therapy in premenopausal Australian patients