I was on Letrozole, initially for five years but before that time was up my oncologist suggested that recent research showed better results for ten years. I remember looking at some research papers at the time. I was also advised (may have changed in the intervening six years) that there was no reliable research on the benefits of seven or eight years. I completed ten years on Letrozole. I’m NED, my bone density (originally terrific for my age) is now pretty average for my age but then, I’m ten years older and 79! No aches, joint issues while on Letrozole.
