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TCH's avatar
TCH
New member
14 hours ago

? Chemotherapy

Please HELP!!

Hi everyone, i am 45 years old and i have recently been diagnosed with;

ER positive 
Ki-67 positive
Tumour size 12mm
Toumour has been surgically removed 6 weeks ago with clear margins from right breast.
Tumour grade 3
2 x Negative nodes

I was told that i need radiation therapy and endocrine therapy. But i was given the option to decide if i want to have chemo as well! I am really struggling with making this decision whether i should have chemotherapy or not. Or do i just do Radiation and endocrine therapy. I was wandering if anyone has been in similar situation as me and how did they decide on treatment plan?

4 Replies

  • Hi TCH- that sounds like a difficult decision. My situation is a bit different as the oncologist recommended chemotherapy for me (stage 2; grade 2/3; premenopausal). She was able to see on her computer the likely survival benefit chemotherapy would give in my situation and it was over the threshold where she would recommend chemotherapy. It may be worth discussing at your next appointment if you have not already done so, the likely benefits and risks in that situation in more detail to see if that would assist. I was also offered oncotype testing but decided against it as in my situation it would not have changed the treatment. Perhaps in a case like yours, it would be worth considering that test to get more detailed information on the risk of recurrence to help inform your decision. Wishing you well with your treatment :)

    • TCH's avatar
      TCH
      New member

      Thank you for your response that’s great advice :) 

      My breast predict was;

      surgery only 82%
      +hirmone therapy (4.4%) 87%

      +chemotherapy (2.2%) 89%

  • Hi there TCH​, What was you ki67 number? Mine was very high and unfortunately even though I had chemo, the cancer metastasised 3 yrs down the track. My original bc was ER and pr positive, her2 negative, grade 3 cells, 17mm tumor, no lymph involvement but ki67 was at about 70% so very high. I had a lumpectomy with clear margins, radium, chemo and hormone suppression but just bloody unlucky with it metastasised 3 yrs later.

    Ask some more questions about your risk profile and likelihood of return so you can weigh it all up.

    I wasn't really given a choice on chemo but I was advised it was my best chance and actually when I was diagnosed with metastatic disease my oncologist was shocked as she said she thought i was over treated with my original bc.  I think that ki67 factor and the grade3 cells are important factors in considering treatment options.

    • TCH's avatar
      TCH
      New member

      Hi Cath and thank you for your response. My Ki67 show staining up to 80%. So that’s pretty high isn’t it! So many factors to consider!

      I am so sorry to hear that for you. It’s all so scary and overwhelming 😞 i wish you all the very best and good luck 🫶🏼