@Locksley So starting my premedication last night with 5 Dexamethasone & 1 Famotidine and then the same dose this morning plus 1 Loratadine 60min before treatment starts, totally dosed up ready, I had an appointment with my oncologist first to talk about possible side effects and how I'm going so far. Then had my Paclitaxel without any allergic reactions at all such a relief it did take a lot longer than getting AC 3.5 hours compared to 2 hours but that's ok as its one of my few outings. So I'm hoping it's a sign of how my next 3 cycles will go.Hope everyone's going good in their treatments.xo

Hi I am now into 7 weeks of this one to go. Had a terrible time on AC only could tolerate 3 of the 4 rounds before it knocked me to the wall. This one has been heaps better for me . Still seeing the oncologist weekly before my chemo as I did worry him with my reactions. It feels good to be on the down hill run with this, even though I have radiation then the 5 years of the tablet medication. But I am focusing this as a positive for me So good this site, hugs xxCheryl

I'm at a similar stage. Although my paclitaxel is weekly for 12 weeks. Each week I have a premed of antihistamine, cimetidine and dexamethasone. I didn't get the dreaded 'allergic' response and my Dexamethasone has been halved from 8mg to 4mg. I don't understand why some people have this drug weekly and some 3 weeks apart.

Thank you for letting me know. Hope all continues to go well. I also don't understand the timing difference. Makes it a little hard to work out. Sending hugs xx

Hi @Abbydog and @Locksley yeah mine is fortnightly I to don't understand either, all I know that mine is dose dense, maybe it comes down to pathology results? I'll put that on my questions list for next oncologist appointment ☺Hugs xo

Dose dense is a more intense (stronger) infusion. Research seems to indicate that a more concentrated hit every two or three weeks is more effective than a weekly (milder) dose. Often patients found a weekly taxane based chemo easier than A/C, possibly because it was a reduced strain on the body. Best wishes.

First cycle of Paclitaxel dose dense

ChezaH
Member
5 years ago

Fern88 said:

@Afraser thank you I'm having my 3rd dose of paclitaxel right now, so far so good 👍
@Ween I hope yor leg pain lessons for you and good that you have a script.
@ChezaH sorry to hear that it gets annoying hay. But best to be safe hugs xo
So after not having my treatment yesterday I had to have another whole dose of premeds which have made my face red they say it's all the steroids lol,
Hugs xo

NOOOOOO
Fern88
Member
5 years ago
@Afraser thank you I'm having my 3rd dose of paclitaxel right now, so far so good 👍
@Ween I hope yor leg pain lessons for you and good that you have a script.
@ChezaH sorry to hear that it gets annoying hay. But best to be safe hugs xo
So after not having my treatment yesterday I had to have another whole dose of premeds which have made my face red they say it's all the steroids lol,
Hugs xo
ChezaH
Member
5 years ago

Fern88 said:

Hi @ween maybe as yours is 12 weeks @ a lower dose I'm guessing? Hi @ChezaH that sounds painful, I asked my oncologist today he said I can try 2 anti-inflammatory pills only once a day & my pain is a result of white cells getting made (from my pegfilgrastim injection) in my bone marrow creating pressure, and this apparently happens in your bigger bones. Isn't it the pits when you get infections and then delays in treatment. Totally understand "let's do this & get it done!" Hi @Afraser so I talked to my oncologist before treatment about my numb & tingling feelings and he decided not to go ahead with today's cycle and wants to reduce my dose by 25% So apparently it gets made up intersate & will be on tomorrows 11am flight, so I'm booked in for 11am tomorrow.
Hugs xo

Hi @fern88, Well not going very well at the moment, went to have chemo today, and the oncologist said I was not well enough to have chemo, so postponed for another week. So I am still saying 6 weeks to go 😢 Hugs Cheryl xx
Ween
Member
5 years ago
Hi Fern I did get the next day injection but that was with my first four doses of more intense chemo. I had every three weeks. My Paclitaxel will go for 12 weeks and my Oncologist assures me the leg pain will lessen I have a script for endone if I need it.
Afraser
Member
5 years ago
Good stuff, good luck with the next round!
Fern88
Member
5 years ago
Hi @ween maybe as yours is 12 weeks @ a lower dose I'm guessing? Hi @ChezaH that sounds painful, I asked my oncologist today he said I can try 2 anti-inflammatory pills only once a day & my pain is a result of white cells getting made (from my pegfilgrastim injection) in my bone marrow creating pressure, and this apparently happens in your bigger bones. Isn't it the pits when you get infections and then delays in treatment. Totally understand "let's do this & get it done!" Hi @Afraser so I talked to my oncologist before treatment about my numb & tingling feelings and he decided not to go ahead with today's cycle and wants to reduce my dose by 25% So apparently it gets made up intersate & will be on tomorrows 11am flight, so I'm booked in for 11am tomorrow.
Hugs xo
ChezaH
Member
5 years ago
I got shooting pains in my head, temple and the side of my jaw, plus bone and muscle pain, the oncologist gave me Endup I think it is called and I take a tablet morning and night, and it stops the pain works well. Just had a two week break as I have had a sinus infection and was on high antibiotics, with only 6 treatments to go I am saying Lets do it !!!!! get it done.
hugs Cheryl
Ween
Member
5 years ago
Thank you so much for your feedback. I’ve not been given anything to take after my treatment. My next treatment is on Tuesday so will speak to my oncologist.
Afraser
Member
5 years ago
Please do talk to your oncologist - paclitaxel or Taxol has peripheral neuropathy as a known side effect, starts with tingling in the toes and fingers. Ask what can be done to reduce this, for example ice treatment, if it still effective with a third dose. PN may be mild and mainly irritating, clearing up after chemo is finished, but it can be more severe and longer lasting so keep an eye on it. Best wishes.
Fern88
Member
5 years ago
Hi @Ween hope your not feeling to sore, do you have pegfilgrastim 24 hrs after your chemo? Few days after chemo my hip, lower back, leg pain got worse before it got better and my fingers & toes had numb & tingly feelings, not feeling to bad after the 1st week. So I wasn't keen to see if it was going to happen again on my 2nd dose of paclitaxel (7th July) well it did and the hip, lower back etc pain was even worse & for longer this time (I wonder if it has any thing to do with the pegfilgrastim I have 24hrs after chemo) didn't notice anything like this on AC though. Fingers & toes funny feelings again. I see my oncologist before my next dose this Tues 21st so will be asking some questions.
Hugs to all xo