Craig Jordan - the 'father of Tamoxifen' and anti-oestrogens has passed away
Craig Jordan (who discovered Selective Estrogen Receptor Modulators (SERMs) and developed breakthrough breast cancer treatments), died June 9, 2024, at his home in Houston, sadly from renal cell carcinoma. He was 76 years old. He was born in the USA but went to the UK as a child & did all of his medical training in the UK but eventually relocated to the USA, where he died. An interesting write up on him, here - apparently Tamoxifen was initially used as contraception (but in fact, it increased fertility!) He applied it to blocking oestrogen in women with breast cancer - and it has been used ever since. https://www.mdanderson.org/newsroom/md-anderson-celebrates-the-life-and-legacy-of-v-craig-jordan-PhD.h00-159698334.html And info from Wikipedia: https://en.wikipedia.org/wiki/V._Craig_JordanTamoxifen
Well woo hoo is what I say! I had seen on the news last weekend that some drugs had been reduced in their end price to us the patients. Well to my surprise I needed to pick up my next pack of Tamoxifen (Sandoz brand) and instead of the usual $38.50 today's price was $19.50!! Woo hoo!! I hope that translates to other drugs that we all have to purchase
Tamoxifen version 4 and a fantastic week
Like a bad movie that should never have had a sequel let alone 3, here goes round 4. i've had another little Tamoxiholiday after getting into quite a serious funk a couple of weeks ago. This time I have ditched everything, the drugs, the drugs to counteract the side effects of the drugs, all the vitamins and supplements as well. I didn't really think they were doing anything anyway after 10 months of taking them. Each time I go off it, the side effects give a little and take a bit longer to kick back in. This time after two weeks, they ALL GAVE UP. I have had the best week ever since D Day. That's right, no hot flushes for a week. No foggy brain. A week of no aches and pains, no creaking clicking joints, no funky mood swings, no hot doona dance (and that was not in a good way either) :smile: Sleep, glorious, unbroken sleep and, even a bit of mojo coming back. :wink: I went for a decent trail ride up through the mountains on my horse and was not crippled the next day. The only thing that didn't return quite as well as it has been previously is my short term memory, which is somewhat disturbing but it's not terribly bad. I've been on a bit of a high actually. So, so good to feel normal again. Kind of like a good drug you want more of :blush: So I am really dragging my feet on popping that pill again. The best thing is that I have been able to do some serious, clear headed thinking and soul searching. I have decided this will be the last time. If I can't get it under control there won't be a version 5. I am content with this decision and am not prepared to spend 10 yrs feeling like a moody, teary, achy, no mojo, foggy space cadet for an extra 6% maybe. If it comes back will I blame myself? I have heard and read of too many recurrences even after doing all the right things for years so I don't think so. I would never have known either way. Quite frankly given the amount of spread that was already there I think I'm going to be pretty lucky if it doesn't reappear even with the drugs. Let's hope the chemo did it's job. That's not meant to sound negative of morbid just realistic. My onc has handed the reins over to me and I am to call him if I want to try any of the other drugs. Apart from that "see you in 6 months". I think he's given up LOL Anyhoo all that being said I really do want to do everything that has been recommended. I am hoping going into it feeling this good in mind and body, and armed with some tips and ammo from my new found friend in the UK , it will get sorted. I am off to have a glass of wine. (ok, it's the third one) So cheers to giving version 4 an absolute red hot crack and slapping this bitch into submission. Thanks you for listening once again lovelies. xoxoxoxo Theme song for the day................White Snake.................Here I go again.
Last round of chemo today
Last round of chemo today and I'm feeling nervous . I feel like the chemo has been my safeguard for three months. My friends all sent me congratulation messages this morning but I'm nott feeling it. Its so terrifying. I will now continue with herceptin and commence Tamoxifen in a few weeks. Im now concerned about the side effects with tamoxifen.Tamoxifen supply trouble
Howdy all, Well who woulda thought I would be complaining about not being able to get this drug. LOl Ok, well not the drug itself but the Novladex D brand. As it is the only brand that does not make me want to jump off the nearest bridge I'd be loathe to change...actually I just wouldn't, I've tried the others and they all stink for me. Not sure what the status is in the rest of the country but Brisbane and Ipswich seem to be pretty short on supply with back orders not expected until June/July. I spent yesterday morning on the phone ringing around after my 4 local pharmacies could not supply. About 20 phone calls later I tracked some down about 30k's away and they were nice enough to dispense one of the repeats as well. They wouldn't allow three lots at once though :neutral: So if this is your brand you may want to check out the availabilty sooner than later. xoxoxoxxo
Hormone therapy, it will be ok. :)
I have done 2 years of Tamoxifen and I lasted 3 months of Letrozole. In all that time I have been unable to work and have been too lethargic to do much at all. Yes I was one of the few who had pretty bad side effects and it was really getting me down. I was thinking is this my whole life now? This aching body, is it permanent? Well I have gone off the Letrozole for three weeks. Only a couple of days in to it but I have energy! The aches are gone! I feel fan-flaming-tastic! I am gonna be ok. <3Tamoxifen..a small nightmare, but are the alternatives better
Hello, I am one of the lucky ones..lumpectomy, sentinel node, chemo and radiation, all of which I flew through, running each day, exercising, trying to get back to the old me. I started Tamoxifen September 2016, and managed to get to January 2017, where I told the oncologist it was painful on my joints, a bit of oedema in my legs, I had stopped running because it hurt, I shuffled at night and could I take a break. We negotiated a 3 weeks on tamoxifen/1 week off regime and that gave me the ability to survive it. I was also becoming a teary anxious mess, effecting my work, and life in general. 12 months ago I took time out to look after my mental health to deal with multiple impacts on my mental well being. I saw the oncologist a few months ago, and he asked how i was...breast is fine, but I couldn't manage my head space. Blood test indicated I am through menopause, and he suggested I try Arimidex, as some people cannot take Tamoxifen. I looked at the side effects of Arimidex, and all I can see is mood disturbances, depression, bone pain, arthritis...all the challenges I am currently having. I had a 6 week break from Tamoxifen, and wow...I felt like a new woman...mobile, pain free, clarity in my thoughts. I am too scared to try Arimidex in-case it is worse, so have started back on Tamoxifen. I really want to go off any drugs. Does anyone have any suggestions, ideas, insight please.
