Letrozole Ladies
Hi all, I have been on Letrozole for 7 weeks now. I am finding the side effects a little rough such as constant fatigue, some nausea, bone pain and upset tummy. What are others experience with this medication and do the side effects settle? I cant change meds as I need this one for a clinical trial.
Dr Liz O'Riordan talks about her surgeries & aftermath - A UK Breast Surgeon with Breast Cancer
Dr Liz O'Riordan was diagnosed with breast cancer some years after qualifying as a breast cancer surgeon & realised that whilst she knew some of the physical effects of Breast Cancer surgery - she really was not prepared for the psychological (and indeed actual physical limitations) that she experienced, once she'd had her own surgery, chemo, rads etc - she also suffered from extreme cording that restricted her arm movement. Eventually, after a recurrence and more surgery, it prevented her from continuing as a Breast Surgeon. This is a more recent write up : https://www.nzherald.co.nz/lifestyle/dr-liz-oriordan-im-a-breast-cancer-surgeon-this-is-what-surviving-cancer-myself-taught-me/GWGO5EWTRNFAHB7MLHU5SGPTIM/ In her own 'blog' - she writes candidly - from her own diagnosis, surgery, chemo, tabs & treatment overall with all the same fears and side effects that many of us have experienced .... Read her personal story here (then click on her 'blog': http://liz.oriordan.co.uk/ You can follow her on Instagram too https://www.instagram.com/oriordanliz - work your way thru her videos ..... they are authentic & helpful She has announced a New trial in the UK, attempting to identify younger women with higher risk of breast cancer BEFORE diagnosis - particularly those with dense breast tissue .... leading to earlier intensive testing before the 'normal age' of 40 https://www.instagram.com ; /p/Ct_-RRUINgJ/. (copy & join these 2 parts of the link, to see it as it won't load here.) Nina Lopez (who Liz interviews in one of the videos - add 'this link' after the '.instagram.com bit ... p/Ct2ESwoIkwn/) who talks about HER triple Negative BC here: https://www.the-c-list.com/stories/nina-lopez-39-shares-her-story-of-motherhood-treatment-and-resilience-as-she-lives-with-secondary-breast-cancer And below, are some of the subjects that she covers on Instagram ..
First dose Palbociclib down the hatch... Pallas trial
For those who have an interest in clinical trials or the drug Palbociclib... The Pallas trial follows early er+ bc ladies at high risk of recurrance. The drug, Palbociclib, is given alongside hormone drugs for 2 years to one group, whilst the other has just hormone drugs alone to see how well Palbociclib is tollerated and if it can help prevent recurrance. So, just when I thought I'd done all I could to keep my cancer from returning, I was invited to participate in the trial. There are some possible unpleasant side effects from the drug, so not an easy choice. I got randomised to the drug group, and away we go with the trial that I was soooo hesitant to join. After a lot of fumbling around to get the right blood tests through the lab, and several hours waiting around for results, I got the go ahead. First dose taken this evening and so far so good. Hoping not to wake up shitting or spewing. I was feeling fairly guilty about getting this drug on the trial, as I know there are stage 4 gals out there desperately wanting access to this wonder drug, which is not on the pbs and thousands a month. My treating team were able to reassure me, though, that the more research etc is done, the better the chances of Palbo getting on the pbs. I hope in some small kind of way my participation aids bc treatment for future patients. We all know how important research is and has been at giving us hopeful futures.
Clinical Trial
Hi Everyone, Im currently taking oral chemotherapy due to more bony mets. Thank goodness it hasn't spread elsewhere. My tumour count flew up to 232, having not gone down since October last year, very frustrating. My oncologist has referred me yo Peter McCallum hospital and I'm due to hear from a doctor this week to discuss what is available for me. Does anyone have advice about what is involved with a clinical trial? It would be fantastic if someone has experience, or is involved in a trial. Cuddles, Trace
Venetoclax Clinical Trials
Hello everyone, I heard about this research on Friday last week and have posted some information below. It sounds like a very interesting clinical trial, in the very early stages and aimed at assessing safety. We will keep our members updated about any other developments regarding this research. If you would like more information about the clinical trial, please speak with your medical oncologist. See link below to the article https://www.news.com.au/national/breaking-news/melbourne-researchers-breast-cancer-leap/news-story/bb8aad8401fe2e765a7ecce530698314.Triple negative metastatic breast cancer in brain
Hi all My Mum is currently living with mTNBC which is in her bones and late last year moved to her brain. She has had one treatment of whole brain radiation therapy and continues to be treated with chemotherapy also for the rest of her body. Is anyone familiar with any trials or new treatment options available to women in a similar situation? Mum is based in Melbourne, but we are open to looking whenever is needed. I would appreciate only positive stories to be shared in response to the question, as you can appreciate it is a very specific diagnosis and a difficult one at that so we are trying to remain hopeful. Can anyone relate to a similar diagnosis and have any suggestions? ThanksNATALEE trial
New thread to discuss the NATALEE trial (double blinded study evaluating use of CDK4 inhibitor in hormone positive early BC) Feel free to post if you are likely to enrol/have already enrolled :) My Oncologists have said I am a good candidate and I would like to do my bit for the future treatment options, so am hopeful to get accepted. Supposedly coming to my hospital September ish. Already commenced in US.Trials
I heard this segment on ABC Nightlife last night. It's always interesting to learn about clinical trials and achievements. A caller brought up Tamoxifen Listen to the lady from Adelaide.....what an inspiration "What is a clinical trial? - Nightlife - ABC Radio" https://www.abc.net.au/radio/programs/nightlife/clinical-trials/13460910
