Forum Discussion

Marina11's avatar
Marina11
Member
9 years ago

Paclitaxel side effects

Hi all. This is my first post.
I am triple negative and have had surgery to remove lump & two lymph nodes which were clear. I've finished four rounds of AC and have had three rounds of paclitaxel with 9 to go. This has been such a roller coaster ride of emotions and fear. First the AC either constipated me with a bloated stomach or made my head bang in pain.  
Now I'm finding paclitaxel is not too bad (at the moment) with a rash on my arms, legs & chest and I've  got a little tingle in my fingers but the side effect that is really annoying is the diarrhoea. Or at times the loose motions! My oncologist told me not to have too much fibre in my diet, but if the chemo triggers this effect does it make a difference what you eat. 
Has anyone else had this problem and how did you cope. 
I've had two trips to hospital because of it!!
Any advice would be wonderful..
 Is paclitaxel and taxol the same thing? 
  • Marina it is hard and so isolating this journey i did 4 Fec and it was really hard and then 8 taxol. I was very ill through chemo. Taxol is paclitaxel and i found it got worse week after week as i suffered nerve, muscle and bone pain. No diahharea though. I did a rehab through the Epworth and it was great!!! But 6 months post chemo i was. Im 14 months post chemo now and its great! Theres light at the end of the tunnel hang in there. Day at a time and we are all here to talk and support
  • Hi everyone,
    Thanks for your advice. I'm just going to have to take it one day at a time with the diarrhoea. Makes life that little bit harder when you have to second guess everything you put in your mouth! The doctor doesn't like me taking grastro stop because it may cause constipation. Vicious cycle!!
    And yes after I finish the last 8 Taxol I have 5 weeks of radiation!! But someone told me that there are side effects with this too.. oh my.... I'm so over it already!!
    I'm in awe at those of you who have completed their treatments. Doesn't feel like its ever going to end. The AC was really hard and now Taxol! 
    Ive been a bit down so I've enrolled into YMCA Encore exercise class for breast cancer women.
    Hoping it gives me a chance to meet other women. Not sure where else I can join.
    My friends are great but they don't understand how hard it is mentally & physically.
    im sure you all have felt alone at times. I've driven my poor husband crazy with my dependence on him.. Now I'm on Taxol he has gone back to work so I'm home alone, too much time to think.
    But my daughter is expecting her second child in 5 weeks and I'm hoping I'm well and able to enjoy the birth of my third grandchild.
    Anyhow that's enough whining from me.
    I just want to be normal again and have my life back.

  • I never experienced tummy problems while having treatment. I'm also triple neg. however since finishing treatment I have experienced lots of tummy problems. My oncologist ask me to take  nexium whilst having treatment  (for reflux) but because I didn't have reflux I didn't take it,  turned out I had silent reflux and it did some damage.....now I take  Nexium.  I'm also on buscapan for tummy spasms. I think the treatment does damage the gut area....but remember we are all different and this may not happen to you.  
    With the numbness in fingers & toes.  The oncologist kept a close eye on this & when my toes  started to feel a bit numb she cut the dosage back slightly which helped. I finished chemo last April 2015 and the feeling is starting to return even though it wasn't too bad.
    will you be requiring Radiothreapy?
    Take care And remember to look after yourself. 
    Anne-Marie
  • I had loose bowels day 3 to 4 from about halfways through. Perhaps an urgent dietitian referral might be a good idea regarding foods. Bland plain stuff and white rice...which sort of slows the gut down as a bulking agent without too much fibre might help meantime. Avoid spices etc. As it burns all the way through. Hope things improve.
  • Hi Marina1, I had 4 AC & having my final 12th round of Taxol on Friday! I have had intermittent diarrhoea but not serious enough to take anything. It usually settles on its own. Some rounds I have had aches & pains & others nothing.  I have a bit of numbness but it comes & goes so am determined to finish. If he diarrhoea continues you will need to take something, all the best.
  • Hi there...I've also had 12 weeks of AC and have had 7 doses of Paclitaxel, another 5 to go. I also get the trots...big time... after each session. Terrible gripes too and the ozone layer takes a massive hit too from the (very) smelly wind!! I pretty much just push the fluids +++ and have resorted to Gastrostop. I get small blisters on the backs of my hands and the sides of my fingers, typically on about day three or four, but not too badly. Also have tingling and numbness in fingers and toes, but again, not too badly.

  • Yes Taxol is a brand name for Paclitaxel. Can't help with the diarrhoea, but just watch the tingly fingers. It can get worse and can take a long time to recover. Your oncologist or oncology nurses can probably suggest some ways to help if it continues. Good luck.