Hi there...I've also had 12 weeks of AC and have had 7 doses of Paclitaxel, another 5 to go. I also get the trots...big time... after each session. Terrible gripes too and the ozone layer takes a massive hit too from the (very) smelly wind!! I pretty much just push the fluids +++ and have resorted to Gastrostop. I get small blisters on the backs of my hands and the sides of my fingers, typically on about day three or four, but not too badly. Also have tingling and numbness in fingers and toes, but again, not too badly.