Recent MBC - sternum

Hi @Georgie17, Sorry to hear your news and to have to welcome you to the MBC club. I was diagnosed almost 4 years ago. My mets were bone only, located in and around my hip. At that stage Ribociclib or Pablociclib were not available except on trial. So I immediately had my ovaries removed (very simple key whole surgery that only required an O/N in hospital) and then went on a trial with Fulvestrant +/- Ribociclib. They think I was in the trial arm without Ribociclib and I progressed during the two months I was on the trial and had to stop. I then had a mastectomy and have been on quite a few different drugs since. I am currently on a trial using Amebaciclib (similar to Ribociclib) and have been very stable for about 12 months now. If you decide to come of Tamoxifen, I would recommend having your ovaries removed - saves having to have more medication/injections (which is tiresome for me - I currently take 11 tablets/day and have a monthly injection). Women are having fabulous results with Ribociclib with the main side effect being low neutrophils. Amebaciclib doesn't have such a problem with low neutrophils, but causes horrible diarrhoea. Hence I taken anti-diarrhoea medication as well. Also, they may want you to go on a monthly injection of Denosumab. This is a relatively new drug that helps prevent bone loss (and in the case of damaged bone, helps repair the bone) and prevents bone breakage. I have been having this injection since diagnosis and the side effects are minimal (just feel really tired for about 3 days). Good luck with your decisions and here's to many years of living well (even though we have bone mets)!!! Lisa xxx