Kisquali and Xgeva

Kiahdee

Hi everyone, 
I’m starting Kisquali tablets and Xgeva injections next Tuesday. 

I’m already having Zoladex injections and take Aromasin 1 x day. 

I was wondering what side effects anyone has experienced with Xgeva and Kisquali?  

My oncologist told me that Kisquali could cause sore hands and feet, nausea and low blood counts. I’m to take it for 3 weeks and have a week off, and recommence the cycle again.( He told me it’s not chemo, but it sounds a lot like it to me.)
Would appreciate your thoughts.
Thanks Deanna. 

Ali55

Hi Kiahdee
I thought I would write the response that I would have liked to have been able to read last year.  I am now on my 16th cycle of Kisqali with Letrozole and regular Xgeva and it is going great . I have found it not a bit like chemo - tablets in the morning and the occasional injection. When I first started taking this combo I was a little tired But after about the 4th cycle that too stopped being an issue. My hair has thinned a little so I have cut it short. I can exercise, work and travel. I feel very privileged to be able to be on this  drug combo so I hope you also have a good and strong response too. I am only having scans six monthly after my lesions in liver, lungs and bones shrunk after the first 6 cycles. I am getting on with living , Good luck 😉 cheers Ali

Ali55

Hi Kiahdee I forgot to mention that yes I do have a drop in white blood cells most cycles but it usually jumps back up within a couple of days and I have not had any more colds than usual ! Best wishes Ali

Kiahdee

Thanks Ali, 
Thats very comforting. That makes me feel better coming into next week, when it all starts. No wonder you would have liked that response last year. 

Im so pleased your responding well. 

Here’s to living! 

Deanna. 😄

Palmbeachprincess

Hi,

i was on zolodex, massive needle, luckily I have plenty of tummy roles so was nt too painful. I opted to have my ovaries removed so no longer require zolodex. 
I also have xgeva monthly. Easy, in the tummy. No side effects from either. 

Hankster

I had a bad reaction to xgeva it ate away at my jaw and I lost 5 teeth 

Glynnis

@Kiahdee I too am on kisqali and letrozole, have had hair thinning, which only just started so like @Ali55 cut my hair short, actualy super short lol, lost my eyebrowswhich doesn't bother me as I wear glasses so not so noticeable,  been getting occasional nausea about half hour after taking tablets, dry skin, shocking nails but it's doing what it is suppose too by keeping my cancer in my bones under control, I work part time, yes get tired but just go to bed early lol, I've been taking it now for 8 months, if it keeps me alive then hey ill take it I can deal with the side effects. Hope all goes well for you 😀😀😀

Ellamary98

Hi @Kiahdee. I have been on Kisqali and Letrozole for 16 months and feel very blessed. This drug combo has been very easy on me and has thus far done an amazing job of reducing my lesions in bones and liver. I am now down to 2 tablets of Kisqali for 2 weeks, then a week off. This seems to be my sweet spot, after suffering from low white cell counts on the full dosage. I have blood test monthly and scans every 6 months. I see my onc every 2 months. I run, I work full-time, and I keep up (mostly) with a busy, full household. My hair is a little thinner, so like @Glynnis I cut it very short. Overall, I feel brilliant and I almost forget that I have a chronic illness. Good Luck!!

Glynnis

Like you @Ellamary98 bar side effects which are more annoying than anything else, I feel great 

Kiahdee

@Ellamary98 Thank you for sharing. That makes me feel more confident heading forward. I've had 3 cycles of Kisqali, 3 tablets a day for 3 weeks and then 1 week off. All my blood results have been ok. Last blood test was 18 December. But I ended up in Emergency Department yesterday as I was feeling awful and felt something wasn't right. Been unwell since Christmas eve actually. Long story short, white cell counts low and I've had an injection to boost white cells. Had bone pain since the injection though and that will pass, so lying very low. I'm off Kisqali now until I see my oncologist on 15 Jan, I'd say my dosage will be reassessed like yours. My oncologist on holidays, so relief onc took me off the kisqali. Luckily no fevers. I have a tumour on both hips and one on thoracic spine. Scans on 6 Jan too. So I shall see what happens in next fortnight. Don't recommend having low white blood cells, not nice!  @Glynnis I keep my hair short now too, its definitely thinner but that's all good, much cooler! Thanks for your support ladies. Deanna xx

 

Glynnis

@Kiahdee I agree my hair was really thick and heavy now it's really short so so much cooler and don't need to do anything with it 😀

Silba

Xgeva for 12 months now, really painful all over bone pain for 2 days after injection, hair is thinning and teeth hurt ( no cavities )but after that it settles to manageable with Fenpatch and Panadol Osteo, I too have a tumor in the pelvis and had a hip replacement 4 months ago, but the pain after  injection is an all over hard to describe, but it's keeping me alive along with the tamoxifen.