Paclitaxel
I’m have trouble with my feet and hands after the forth treatment of Paclitaxel. My oncologist is talking about stopping it altogether. I still have 8 more treatments to go and was wondering if anyone has any idea what treatment they would give as an alternative. I was diagnosed with triple negative. Any thoughts would be really appreciated.
Docetaxel side effects
My next 4 chemos are docetaxel. Its side effects are really scaring me. Has anyone else had it and how bad was it? Does it make you loose hair as I have been doing the cold cap and dont want to waste all that time and stress. Also I've heard it can cause neuropathy, and some use ice to stop it. Any info would be greatly appreciated. Ican see me sitting there with a cold cap , and hands and feet in ice!😲👣🖐😨
Neuropathy with Taxol
Hi, I was diagnosed with 3cm Hormone positive, Her2 negative, ki67 of 40% breast tumour with no nodal involvement in June. Because of size and my wish to avoid mastectomy I went with neoadjuvant chemotherapy. First I joined a trial for palbocyclib and letrozole but after 1 month, though tumour didn’t grow, 3rd biopsy showed I was in the control as Ki67 was still the same, so my oncologist swapped me to AC-Taxol. 2 weeks into AC, my hair fell out and nails started to change colour. The latter is unusual according to specialist. I got plantar fasciitis week 4 and had to stop walking for 2 weeks : a huge blow - but the rest helped. By the end of AC my toes were so sore! Then I started weekly Taxol. I could barely walk because of my sore toes and residual PF. I keep both finger and toenails very short and finally (when shops opened again) bought a bigger pair of runners! Lovely. With the neuropathy I feel like I’m walking on crushed glass even when I’m lying down, toes numb, toenails very sore, fingernails and fingertips v sore, but the brown cuticle appears to be growing out. Other side effects: anaemia - Haemoglobin of 78 instead of 110-160 (was given blood transfusion last week), wheezy cough, tight chest (ecg and X-ray clear), muscle aches and pains, fatigue. I was so tired after yesterday’s treatment (Taxol week 7) I conked out after dinner, but the wheeze was getting to me so I went for a walk on the beach... and felt better! 😅 I’m worrying about how much of the neuropathy and wheeze is too much? How do I know if the Taxol is causing permanent damage? Yesterday the oncologist says it is my call about how much more Taxol I want to submit to given my side effects, but I’ve no idea how to judge my neuropathy symptoms and wheeze, and am worried about changing to CMF for the 5 remaining weeks.
Paclitaxel Delayed
I was supposed to have my 9th paclitaxel this morning but was cancelled because I have had significant increase in numbness in my hands and some pain in my thumb over the past week,(even after onc reduced last weeks dose by 10%) My feet seem fine at the moment. My regular onc was on leave so the one on duty made that decision and said that they will see how I am next week and decide what is next. I am quite disappointed as I was getting towards the end of the chemo and want to get it over and done with. On the other hand I didn’t want to say everything was ok as I had read on a few threads here of the lasting damage PN can do. Has anyone had a similar experience?
Neuropathy in feet - any advice? TNBC
Hi everyone I've TNBC and am 6 treatments down with the first Carbo/Taxel/immunotherapy regime. For part of my infusions, they put cold gloves on my hands to reduce the risk of neuropathy there, but didn't offer anything for the feet. They suggested I go online and purchase my own cold socks to wear during treatment. Last week my toes started feeling numb and then yesterday my heels started feeling sore when I walked. I walked a bit at the shops this morning and my feet felt odd the whole time. I'm assuming this is all related to neuropathy and I must admit I'm a little freaked out. I've purchased some cold socks now online and will start wearing them during treatment, but I'm worried what damage has been done already. Be interested to hear what experiences others have had with this, what they've done about it and whether it has resolved after treatment finishes. (NB I'm putting this in the general discussion arena as I thought it may not be simply TNBC related?) Kathy
Decision time re continuing Paclitaxel due to peripheral neuropathy - help needed
I have started to have signs of PN on soles of feet after 4 of 9 planned weekly Paclitaxel. Onc has left it to me to decide when to pull the pin. Symptoms are mild atm I think (numbness on soles, slightly tender on rough surfaces, discomfort after 3/4 of my usual 40min walk) but I have no idea how quickly they will progress from this to severe and very long lasting ones like some of you describe in other threads. I am terrified of becoming badly incapacitated after all the effort I have put into exercise and gym to keep mobility, balance and strength as I grow older. Time is so limited to access expert advice between weekly treatments and Christmas and I am scared that even one more dose may tip me over the edge. Is there anyone who was in a similar situation that can perhaps give me some concrete idea of the timing of the progression of their PN from week to week. The onc has said if I say this is all I am prepared to live with for 12 months he will delay the next treatment and see if there is any improvement. If there is he will try one more because it has shown that improvement is possible. If no improvement I will then have to go onto another kind of chemo that takes longer and is more involved (and I guess another swag of side effects 🙄). He says my prognosis would not be affected. Any information will be much appreciated as only a few days before next chemo. 🙁 Thank you!
Peripheral Neuropathy success
(Re posted as requested with new title) Just thought I would share the success I've had with Alpha Lipoec Acid for my peripheral neuropathy. It's an antioxidant support, I've been taking 1 tablet with breakfast and dinner, 400mg (says you can up to 3 a day) suggested by my Med Onc and it has really helped! I hope others may have success with it too xx
Chemo dilemma
Hi just after some input, I have finished 3 rounds of TC chemo, had reactions to all three at time of infusion, although the third one was handled better with increased steroids and antihistamine and a dose reduction but the side effects for the increased steroids was terrible for a number of days. The chemo has left me with 3 quite numb toes and from the first round I have experienced tingling and pins and needles in my feet which has progressively got worse, I had really bad feet pain after round 3 and could not drive or walk properly for days. I am supposed to have one more round of chemo and am reluctant to do it, I have talked over with the onco who says they won't push me to have it as I was in a grey area for the chemo anyhow, with no lymph node involvement but LVI was present and statistically only a 1percent advantage in having it. I am leaning towards not having it as the thought of permanent nerve damage in my feet and hands terrifies me. I have could stats sitting between 87-90 percent that the cancer will not return after my radiation treatment and would just like other people's thoughts....Onco said that 3 treatments would not have been in vain if I don't have the last round, however the stats she has are for people that have completed 4, she also mentioned that it is likely the side effects will have a cumulative effect for round 4, any advice or similar stories would be welcomed my head keeps changing its mind..to do or not to do??
Never say never
https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Peripheral-Neuropathy-Fact-Sheet I was looking for some information on PN just to check how long it may take for improvements to keep happening and found this site, which I think is pretty useful. Most tend to focus on pain relief, which is absolutely fair enough if you have pain, but I don’t and was looking for more info on sensory nerve damage. Because my feet just took another small step forward - absolutely no idea why but good stuff! I can feel most of the area between my soles and my toe tips - doesn’t feel entirely normal but definitely there! Toe tip feeling came back nearly two years ago. I can walk perfectly well, just don’t trust myself running! Happily sensory nerve cells can revitalise themselves it seems. Seven and a bit years and who’s counting! But millimetre by millimetre we are getting there!ALA for PN (Peripheral Neuropathy)
Just thought I would share the success I've had with Alpha Lipoec Acid for my peripheral neuropathy. It's an antioxidant support, I've been taking 1 tablet with breakfast and dinner, 400mg (says you can up to 3 a day) suggested by my Med Onc and it has really helped! I hope others may have success with it too xx