Hi @Angelo, I too was diagnosed with Stage 4 with bone mets out of the blue last Oct 2018. I too am still working full time. Between Oct and now, I've had every possible diagnostic scan, test, bloods, trial and error with some drugs, plus 2 x restaging scans. Its been a bit hectic! lol :) I'm on Letrozole (makes me fatigued somewhat), Ribociclib and Denosumab. My last restaging scans showed the breast lesion has pretty much faded away to nothing and my bone mets seems to be relatively inactive and stable. That's as good as I can hope for, yay! :) I still feel fine, I felt fine before this journey started. When I ask my Onco about progression, he's very non committal as everyone seems to respond differently. Some make it for many more years and others pass sooner. I've also asked my Onco point blank what my prognosis might be, as I too want to plan for when I should stop working. I like my work and I want to keep working, its part of me. My work has been very very accommodating and have "cut me some slack" when I asked for it, given everything I was going thru initially. Have you asked your work also? As to when to stop working, I guess when that time comes, we will know to make that decision. Unfortunately, there is no real formula or rules to follow, as to when might be the "right time". The only thing I'm sure of is that at some time, I will make the call to finish work. I've also found this journey has reframed my thinking somewhat and made me determine what is most important to me. And I've decided that I won't do anything I don't want to do anymore. If you still like working, stay working. If you don't, make the call and enjoy the time you have doing what you like doing best. Best wishes for your journey. Cheers