So sorry that it's come back @Kats162 , I also have been recently diagnosed with stage 4 ( metastatic ) and mine has also returned in the lymph nodes and one spot at the base of my neck C7. I had a big 18 months clear after 15 months of treatment for the 1st bout and am almost on my 6th round of Xeloda ( oral chemo ) which I'm so far tolerating well and follow up scans 3 weeks ago show that the cancer is shrinking. We are definitely on a rollercoaster ride now but I try and stay focused on the now and try not to pre empt or worry too much about the what lies ahead. None of us know how this disease will progress as each of us are different, what treatment works well for someone may not do the same for another. I know that this disease most likely will get me eventually but hey not without one hell of a fight 1st! I guess the longer we stay well and our disease stays controlled the higher the chances of there being that magic cure. It is a really crappy hand to be dealt but we can't change it, it's ok to be scared, angry and to want to hide away from the world sometimes too but in the end living our lives and focussing on all the good stuff is what will get us through, and when that fails there is always wine! Wishing you well with your treatment and know that we are all here if you need us