NATALEE trial

Confirmed today I will be going ahead with trial unless the clinical researchers find a reason I’m not eligible, Onc doesn’t see anything impeding me. Will involve a few more frequent visits to hospital for three years then ideal but as I’ve said, it’s important for the next generation of treatment options. Have decided I will keep my port for the bloods needing to be done regularly until my veins return in my one arm avail, unless I have an issue with my port in the mean time.
Only thing bad about trial is it reduces the types of AI I can be on to Letrozole and Anastrazole only.. I suppose if I have issues with this over time I will disenrol from trial and have a try at another therapy. 

Good luck with it @youngdogmum

I’m very hopeful for the next generation of BC patients, CDK4 inhibitors are already showing good results in patients with hormone positive stage 4 disease, the theory that this will prevent or delay metastasis by years and years sounds promising. I really hope it works and that in 20 years time some other 27 year old will be told, it’s okay we’ve got this drug. 

@sister there’s a lot on line and being conducted at FMC.Here’s a bit about it .

NATALEE with ribociclib 

A study of endocrine therapy with ribociclib (CDK4/6 inhibitor) in patients with high-risk early-stage hormone receptor positive breast cancer following surgery. 

• Requirements: patients with high risk early-stage breast cancer which is hormone receptor positive, HER2 receptor negative and have undergone breast surgery, within 12 months of commencing adjuvant endocrine therapy.

I haven't heard anything about it but interested to hear more.