I agree with Kath and Cyclo. It's hard to sort out what is stress, fatigue or side effects from the drugs. Three months into Letrazole, I'm still very tired, stiff and sore, but gradually getting better. Exercise really does help. To start with, I thought I was wearing myself out by walking in the morning, then I figured out that I felt like shite by mid afternoon regardless of what I had done in the morning. Overall, getting my body moving again has helped my mood and made me a bit more optimistic about recovering a bit more.