Is someone going with you? The immediate response is that it is very hard to tell how you will respond, but if you feel unwell in any way having someone with you is a practical consideration. I had my first chemo in hospital (side story) so anyone necessary was on hand, and no need for anyone to supervise me getting home etc. I did all my chemo solo from them on as I knew I was fine. Other than that it can be slow, so music, reading material etc. You may be next to someone who wants to chat, but often people are either with friends and family themselves, or choose to occupy themselves. You'll be offered tea or coffee and probably a snack, but take your own if you prefer. Best wishes.