Forum Discussion

Michele_B's avatar
Michele_B
Member
6 years ago

Prolia iv

Hi all, have recently been changed from Tamoxifen to arimidex because of ongoing gynae issues. My gp suggested I have a bone density scan as a baseline. Turns out I already have osteoporosis in lumbar spine.  He is keen for me to have an iv drip of prolia. Anybody else gone down this track please, and what were side effects?
It really is one thing after another , isn't it. Hugs to all out there, x
  • Thanks @Romla and everyone else for this information.  I really hadn't heard much about prolia before and was a bit hesitant to add yet another thing to the regime. Sounds all quite positive tho so much happier about it all. Thanks again xxx

  • Zolendronic acid goes by the brand names Aclasta and Zometa
  • Here is an article about Prolia and breast cancer.

    https://www.breastcancer.org/research-news/prolia-reduces-recurrence-risk-for-some

    I have been on Prolia for 2 years now.It is a simple painless injection into the abdomen every 6 months and have had no problems or side effects.Many women have it not only for osteoporosis but also arthritis.I was worried when I was told I would have to have it but was quite surprised how many women I know have it regularly , all with no issue.

    I need to say I was temporarily on bisphosphonate tablets some years ago and needed an extraction.I found it very difficult to get help due to dentist fear of osteonecrosis of the jaw and litigation.Finally I receiv3d help from Professor Goss who had the chair in dentistry at our Uni but only after cross laps testing to ensure bone was still turning over - it was .

    Be careful with bisphosphonates be it by tablet or iv.
  • I think there is confusion between Prolia - a 6 monthly injection and Zolendronic acid delivered by iv. Personally I wouldn’t accept the latter as is a bisphosphonate.

    With Prolia it exits the body totally after 6 months enabling dental work to be done safely between injections.Bisphosphonates stay in the body continuously and many dentists are reluctant to help you if you need an extraction or root canal because of the risk of osteonecrosis of the jaw.

    Have a look at the Australian Osteoporosis website and ask plenty of questions of medical staff.I urge caution and talk to your oncologist maybe even a specialist in the field of osteoporosis not your GP.

    Re costs of Prolia .If you’ve been diagnosed with osteoporosis and are either over 70 or had had an osteoporotic fracture ( not sure if that includes toes) the cost is around $38, if not it is around $275.Prolia also  is acknowledged as reducing bc recurrence risk.

    Regardless of the choice you make have a thorough dental check before starting either and ensure all dental work is up to date.
  • Thanks so much for this @Irb_0 and @melclarity, that is really reassuring info. I hadn't heard of the IV either but gp was insistent that would be the way to go, and only every 12 months. He dis mentio  the cost @melclarity, but then said, given I broke a toe a few weeks back when a student accidentally sat her chair on it, said that should satisfy criteria. If not, i will pay, if it makes a difference it will certainly be worth it. Thanks again, so much. I was worried  about more side effects but this sounds promising. Big hugs back to you both. Xxx
  • @"Michele B"  at the end of my chemo treatment end of 2015 I had a bone density scan which showed I had osteoporosis in my neck and lower back. I've been on Prolia injections for 3 yrs every 6 months, they have made an incredible difference!!! I cannot recommend it enough. The injection is not a big deal, I do however feel a bit off for a day or so, sort of paining throughout, but that's it. I am no longer osteoporotic :) Im due to have my last one around now. There is another little added benefit, this combined with an AI adds extra protection to a recurrence!!!! go figure, they dont quite know why but it does :) 

    There is however a criteria, if you havent had a cracked rib or fracture of any sort and are under 70 you will have to pay. It costs me a few hundred dollars but my extras NIB covers some of it. We tried challenging it but I was late 40's when I started and unless you fit the criteria it will be out of pocket.

    I havent heard of it as an IV??? the injection is super easy as I said and only every 6 months.

    Hugs M x Thanks @iserbrown hugs to you xx
  • I've not long had my first prolia injection,  but it was subcutaneous not IV. After 3 years on AI's(2 different ones) I went from a very normal bone density in my lumbar spine  to mid range Osteopaenia in 16 months. My hip measurements while decreased, were not as dramatic and still in normal range 

    With osteoporosis you will get it at PBS prescription price. It's twice a year and can be given by a practice nurse very easily.  Didn't hurt at all.

    A couple of weeks after I started getting some increased lower back and hip pain. This lasted  a good few weeks. At the moment I'm not sure if I'm just getting used to it, or if it's improving at the moment. Hopefully the latter. 
    I haven't noticed anything else at rhis point. I only hope it works 🤞🤞🤞
  • Thanks @iserbrown, will be great if someone has some info for me.
    Cheers
  • @melclarity
    From memory can add some light on this topic
    Take care