Thanks so much for this @Irb_0 and @melclarity, that is really reassuring info. I hadn't heard of the IV either but gp was insistent that would be the way to go, and only every 12 months. He dis mentio the cost @melclarity, but then said, given I broke a toe a few weeks back when a student accidentally sat her chair on it, said that should satisfy criteria. If not, i will pay, if it makes a difference it will certainly be worth it. Thanks again, so much. I was worried about more side effects but this sounds promising. Big hugs back to you both. Xxx