Palbociclib -new side effects from tablets
I have MBC and have been on Palbociclib (Ibrance) and Letrozole for 30 months. I have tolerated it fairly well aside from some fatigue. Last month the Ibrance capsules were replaced by tablets. I have had severe nausea and stomach cramps with dizziness and hot flushing since changing to the tablets. Has anyone else experienced a change in side effects with a change to the tablets?
Metastatic cancer
God I’m over feeling the way I do started Letrozole and Palbociclib tablets this morn and have t been sick but god it’s taking toll on body feeling bit buggered ... stomach is full nerves as suffer from anxiety and panic so get feeling of word and scared like u want to b sick then it goes ... is this normal will it get better each day or worse I keep thinking worse try to relax and I can’t god wish I could turn back time don’t even know how I’m gonna take tablets in morn if I keep feeling like this plus need to get calcium tablet god only knows how I’m gonna take that too feel like giving up alreadyHerceptin, Palbociclib and Letrozole combination
Hi everyone, this is the first time I have posted in this forum, so hello :) I am currently doing 18 weeks of chemo and 3 weekly herceptin treatments, and my scans are showing that the cancers, which are in my liver, lungs, bones and lymph nodes, are reducing quite a lot. So far I am at week 13 of treatment and some days I am really struggling to cope with all the yucky chemo side effects. When my 18 weeks are up, my oncologist has suggested I go on a trial for Palbociclib as well as Letrozole and continue with the herceptin. I am pre-menopausal and 45 years of age so I think that's why I'm eligible for the trial. Anyway, I have read all the side effects of Palbociclib and Letrozole and it really scares me. Is there anyone here who is currently using this combination of therapy and can you please tell me your thoughts / experience? many thanks xxpalbociclib now on pbs as of may 1st
Hi everyone, woo hoo, the government has finally put palbociclib on the pbs as of may 1st 2020 it will become available. I do not know if there are any set criteria for this ie only for those on a first line of treatment as has been the case in the past,. I have tried for several years for this to happen and finally the government has seen fit to do this. I do hope this is now available for ALL women regardless of where they are in their metastatic treatment. wendy55
CDK4/6 inhibitors PBS
Hi, Can someone share their experience or knowledge of who can access CDK4/6 inhibitors? I’m trying to establish what my situation would be in the current PBS environment if I became stage 4. I am on an AI for endocrine therapy. The wording in the PBS documents is unclear it says exclusion criteria - treated with AI for more than 28 days. Is this for mets though or all stage cancers? Given that AI is now preferred choice of endocrine therapy for hormone positive cancer, does this mean if those of us on AI for early stage would not be able to use palbo, ribo or abemociclib if we progressed to stage 4 under PBS ruling and would need to self fund? Thanks everyone.
Palbociclib
Please excuse my spelling guys, the names of these drugs do my head in! I have a friend who is currently taking this medication as a last attempt at slowing the progression of her metastatic cancer, she has been paying for this drug since the 26th of Feb out of her own pocket - 5k a month...it is now on the pbs from the 1st May but she doesn't qualify as she isn't a new patient. What the?. This drug is helping her surely there is some way of getting her access to it without her having to pay the exorbitant monthly price she currently is...if any of you have any ideas on how I might be able to get some help for on this I'd really appreciate it @Zoffiel I know you usually are pretty up to speed on the politics of these things? Thanks for any advice
Two steps forward, one step back – news on access to CDKs in second line treatment
Hello everyone, BCNA has an update on access to CDKs as second line treatment. Pfizer have this week advised BCNA about a new capped access program for the CDK inhibitor palbociclib (lbrance) which will be available from October 1, 2018. This means you still have to pay for around 8 months of treatment (at a cost of around $40000) but after that time it will be free. We understand that this is still a huge cost but it is an important step forward because people will at least know how much they will have to find should they want to proceed with this line of treatment. BCNA is continuing to work for our members in this space and we’re very pleased to be able to advise that we have been able to negotiate with Pfizer that anyone who can show that they have already paid $40000 (for either first or second line treatment) can immediately move across to the capped program and no longer have to pay. For further information, go to our website. Please help us share the news to anyone you know who may currently be paying for Palbociclib.
