Hi @mumma4, AIs can certainly cause joint pain so seeing a rheumatologist will be helpful. I did have some pain on Letrozole but I was fortunately that it settled for me. I am not on Letrozole now due to progression. In terms of medicinal cannabis it sure helps many people. It's an individual choice but it does work for many people and there are many places it is accessible now, even online. There are a few members on here that have had success with it, including myself. It's can also be helpful for sleep too. Pain is exhausting and I hope you get your pain uncontrol.