Hi Josephine, am also on letrazole since about March and also have the joint pain particularly worse during the night. Once I’m mobile during the day I dont notice it so much. It seems to affect different areas at different times started worst in my legs also now just bit stiff if sat for too long. Then got bad in my finger joints and at the moment I have a particularly sore area at side of my wrist it hurts so bad to wipe my bum during the night (sorry for that info lol) my onco said if it ever got too much I could change to another med. I get fairly minimal hot flushes which I hate so worry could be worse off. I don’t know just scares me this is for at least 5 years 😫