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Joint issues or rheumatoid arthritis?
After 5 months of Letrozole and now a 3 week holiday from it because of developing very sore trigger fingers in both hands that has now increased to thumbs and wrists with persistent bone aches, my GP...
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I also tolerated Letrozole for 6 months, and in that time I plummeted into depression, and was so stiff, with a lot of joint stiffness and muscle aches, I could hardly wipe my own bottom (TMI), true story. So my oncologist suggested trying another AI. There are other AI's equally effective that may be more suitable for you.