@Lisa1407 I did Trodelvy for 4 months earlier this year, from Jan thru to early May. I had 12 infusions/6 cycles. I think I stayed on the full dose the whole time. Yes, I was fatigued, but it was really the initial infusions that wiped me out; it got better with later cycles. You could also try acupuncture before an I/V. I did and found it helped. I also was up & down with diarrhoea and constipation; just kind of got used to having to take senna col or similar to help regulate. And I lost all my hair, but it’s now growing back. The Trodelvy workers well on my bone and skin mets. I’m currently not doing any treatment- having a break and travelling! 😃
good luck with your side effects. If fatigue continues, I would say yes, ask for a lower dose. xx