Complete Metabolic Response De Novo TNBC

In July of 2023 I found a lump. It was a few weeks after turning 38. 5 weeks later I was diagnosed with De Novo TNBC, with lung mets. I didn't have any symptoms that indicated my lungs had cancer in them at the time, but while waiting to see if I was eligible for a clinical trial, and which clinical trial, I developed a cough, struggled to walk quickly and couldn't finish a sentence without forcing the air out. The cancer was so aggressive and "hungry" for my blood, my arm would go numb if I tried to exercise, as the primary tumour wanted it more. I needed treatment ASAP. Life was becoming harder everyday and I wanted that valuable time with my children who were 3 and 6 at the time. I was given 1-2 years to live with usual treatment. 

I went into a clinical trial, Ascent 3. I wasn't suitable for immunotherapy and was lucky enough to be allocated the trial drug, Sacituzumab Govetican, as a first line treatment. 

So it began on the 4th of October. The first dose was wonderful, it felt like a cold cloth on hot sunburn. After the first cycle, I could hug my children without pain in my breast and read a book to them without becoming breathless. I became determined to win, and to beat this dismal disease. I became unrelenting in my pursuit of being cured. 

For a year I was on the highest dose of Sacituzumab Govetican. Most of the lesions in my lungs had resolved, but for 8 months I had 2mm spot that was dormant. It became active again and also cleared.  In October 2024, I had a lumpectomy with clear margins. I continued treatment with no evidence of disease until July 4th, 2025. Eventually my body couldnt take the treatment any longer, and the trial was interfering with my life. Over 21 months, I had 27 cycles of Sacituzumab Govetican.

It's been over a year now, and I've remained in complete metabolic response. I hope I continue to stay this way and eventually be told I'm cured. For now it's been PETs every 3-4 months, but between them I live my life normally.  

I wasn't sure this was the right area to post my story, but hope can be an important symptom when facing dire circumstances.