Triple Negative Metastatic Lung

Hi Mabel, I'm 47 with TNBC that has recurred 3 times now and while my recent surgery got a lot out and they can no longer see on CT scan the pathology showed it was positive margins and it's expected to keep coming back and no current chemos expected to help.  this stuff really sux.  Especially when you have young kids.  I have done a bit of research (as you do when desperate) and while none of it helped me as my tumour doesn't have anything that they can target at the moment, just thought I'd mention some of the testing I had done in case it might help you.  If your tumour has androgen receptors a very new approach has been to use prostrate drugs on it (this is not a standard test to get done you'd probably likely have to ask for it), on another TNBC page one of the ladies went from mets to lungs, liver etc to currently NED 2 years out.  If your tumour has mesothilin on it there is some new clinical trials targeting that.  If your tumour has high PDL-1 then that can help identify appropriate immunotherapies that are more effective.  I also had Foundation One testing done (cost about $4k) while it has identified certain features they do not currently have a treatment approach but I heard there is a clinical trial in Melbourne targeting AKT1 which I'm hoping is successful and leads to further treatment approaches targeting AKT mechanisms because my tumour has very high AKT2 levels.  you may well have discussed all this stuff and current clinical trials etc with your team but just thought I would mention as my oncologist was not up on this stuff and when I kept pushing for info has now referred me on to specialist breast cancer oncologist who has then referred me on to oncologist involved in clinical trials to make sure we are looking at all options and newer treatment possibilities.  Sending gentle hugs