Forum Discussion
Jen001
7 years agoMember
I so very much wish there was preventative medications to stop reoccurrence such as the hormone treatments available to other types of breast cancer, but given TNBC doesn't have hormone expression, there isn't the same targeted theories available. From my understanding TNBC is heterogeneous (big word that sort of means diverse and made of many subtypes) with 6 main sub types currently know and others still being researched.
For me, after neoadjuvant treatment and recent surgery, I am now on a course of oral capecitabine (xeloda) to destroy any micro metastatic cells that might be lurking after the surgery, given I had positive metastatic nodes removed under my arm, (PCR in my breast and no other cancer elsewhere in my body).
My understanding is capecitabine is an existing approved drug in Australia used for treatment of metastatic cancers. There is a recent study in Japan called CREATE-X which had exceptional results from giving capecitabine to people with positive nodes or not receiving PCR after neoadjuvant treatment to increase their disease free survival rates. The results from the study were extremely favorable to TNBC.
I am truly grateful to my surgeon and oncologist for being given capecitabine as my chances of reoccurance after neoadjuvant treatment were much higher than I would have liked (or what the would have liked too). I suspect with the results from the Japanese study the use of the drug will increase for those with TNBC similar to myself.
I would suggest speaking with your oncologist about the CREATE-X study to see if the results and treatment is relevant to you, or perhaps there might be something else.
Wishing you both the best onemargie & duxx1234