Hi there I was diagnosed last September stage 4 de nova er,pr + her 2 negative. At that time it was in my left breast, lymph nodes and bones. I started on Tamoxifen, then letrozole with Riboclclib, Zolodex implant and bone injection monthly. Unfortunately the treatment didn't work and my recent scans showed it's in my liver. I am now awaiting to see if I can go on the Capture trial if all my tests come back ok, I have the PIK3CA mutation. Just wondering has anyone started on the alpelisib and fulvestrant or anyone on the Capecitabine and any bad side effects. It's been a bit of a whirlwind from having no symptoms and just going for my normal mammogram as BC runs in the family and told straight stage 4. I have two teenagers who are amazing and give me plenty of strength. Look forward to hearing from anyone with information. Keep strong my sister's 🥰