Hi @Not_good_63_57, Just wondering if you have mets in your pelvis and/or spine? I do and am having terrible trouble with back and leg pain. I have been going to a physiotherapist at the suggestion of my oncologist. I have been on Letrozole and Denosumab until recently. I am always quick to blame the drugs, but it my case the oncologist wouldn't have a bar of it and suggested the physio! First I was diagnosed with some nerve irritation due to stepping off a ladder and this time I am just seeing the physiology this afternoon. I think it muscular and related to the mets this time, but pain has been so bad I have been taking endone regularly just so I can stand and walk. Hoping that this is not going to be the way of the future for me! The physio has been very helpful for me though and of course a chat to you oncologist will help too. Good luck in finding out what is causing the pain. xx