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Cath62's avatar
Cath62
Member
3 years ago

Letrozole - Fracture in spine

Hi, a couple of weeks ago I posted about pain in my bones in my ribs and needing a bone scan. At the time the doctor was checking on bone mets. 

Well I don't have bone mets which is great but the bone scan revealed a fracture in T9 of my spine and osteoporosis. This is scary because I have not even injured myself. I do recall picking up my 15 month old grandson and feeling pain which prompted me to get more tests done. 

My ongoing treatment is Letrozole. I have only been on this for 6 months after switching from tamoxifen because of adverse side effects from that drug  

I had a bone density taken before I started tamoxifen in November of 2020 and it was perfect at that time. So in the last 2 years of treatment my bone density has taken a big hit. Spontaneous fractures are a bit of a worry. 

My GP gave me an injection today for the osteoporosis which I will now have every 6 months as well as taking vit D and caltrate with K2. I also made an appointment with my oncologist for Tuesday. 

Just wanted to see if fractures have happened to others on AIs?

Also a reminder to keep an eye on bone density. 

21 Replies

  • Bad luck! I will finish ten years on Letrozole in May, and all going well, no fractures. I have had two accidents in that time which might have resulted in problems but all good. My bone density has declined, which is probably partly age but it was very good at the beginning so I hope will see me through. Two years seems a surprisingly short time for such a turnaround. I have been taking vitamin D and caltrate throughout and also as much weight bearing exercise as possible. Best wishes for the injections.