Yes unfortunately chemo throws you into a very abrupt menopause, it is hard and Im 3yrs on and still suffering. Also with Tamoxifen or Arimidex or Aromasin, I had zero effects on Tamoxifen for 4yrs but was pre menopausal. I then had a recurrence at 4yrs same spot and after chemo put on Arimidex, side effects galore. You can trial off any of these but it has to be for a 6 week period as I did under the supervision of my Oncologist. It takes that long to get a true indication of things. I did this with Arimidex and kept a log as instructed. I was then switched to Aromasin which is similar and side effects the same. So I just work with it, its fine. I think my Prolia injections have helped alot strangely as my bone density has improved and in turn I find my pain isnt as bad as it was either..strange.