Hi there, these are certainly hard decisions but two things to remember - most people gain some satisfaction from knowing they have done everything they can to have cancer once, recover and never have it again. Also that you can never know how a treatment will affect you personally until you try it - how it affects others may not apply to you. I’ve been on an AI for over six years - yes, I have some side effects but none of the most common ones - no aches, pains, flushes, etc. You have the right to determine what treatment you have but sometimes it’s worth trying it first before you decide - you can always stop. @kmakm is right - many people here are looking for solutions to side effects. Many who don’t have them may not even enter into those conversations. Best wishes whatever you decide.