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arpie's avatar
arpie
Member
3 years ago

Management of Aromatase Inhibitor–Induced Musculoskeletal Symptoms

There are plenty of Oncologists who STILL dismiss side effects from AIs (Aromatase Inhibitors) as either being a figment of our imagination, or they say/think the side effects aren't as severe as we advise them ..... just print this off & give it to them.  They may learn something!

Aromatase inhibitor–induced musculoskeletal symptoms (AIMSS) were first recognised as a distinct entity in 2001, 5 years after the approval of the first aromatase inhibitor, anastrozole.

(I reckon Carpal Tunnel is about the only symptom/side effect I HAVEN'T had over the last 4.
5 years from the list below ....)

AIMSS can have a protean presentation, most commonly including joint pain and stiffness (including morning stiffness), but also carpal tunnel syndrome (CTS), tenosynovitis, myalgia, and muscle weakness, such as reduced grip strength. Symptoms can be continuous or intermittent and can involve more central joints (spine, hips, shoulders), peripheral joints (elbows, wrists, knees, feet), or both.

You can Read the full report here:

https://ascopubs.org/doi/full/10.1200/OP.20.00113
  • Congratulations! All the best. I am in year 1 of 5 and can’t stand AIs so far…looking ahead to five years is too over-whelming. Trying to stay focused on the day-to-day. 
  • @arpie these days the mere word of an AI causing such side effects in a person sends shudders through me.  As far as side effects go I didn't have success on either Arimidex nor Letrozole. You really can't help but wonder why any woman would imagine all those side effects.  It says a lot about how some medical professionals see women who bring forth side effects and are fobbed off. 

    Thankfully my oncologists were compassionate and understood and never once made me feel I was suffering from a huge imagination.  
  • @Afraser THAT is a milestone worth celebrating !
    👏👏👏
    🎉🎉🎉
    🍾🍾🍾
  • Congrats, @Afraser!!  Please Keep us in the loop!!

  • Well, if there are benefits in stopping an AI after 10 years, I’ll let you know! Last one yesterday!!