The flushes have almost died down to nothing after 9 months of Letrozole so there is hope for you yet. As for good sleep that will take time. My sleep pattern has only gone back to 'normal' a month ago. I feel so more alive! As for your memory try doing crosswords (use a crossword dictionary. My husband calls it cheating but i call it expanding my vocabulary! But then he's been doing crosswords for years so knows all the common clues and answers), sudoku, any sort of puzzle. I found it worked for me. My nemesis is joint pain which has ramped up significantly in the last month. Nurofen is my best friend on bad days. I'm hoping it will back off. As for cholesterol, mine is genetic but I'm able to control it through diet and exercise (gym 3 times a week). If you find you are getting quite sore around your pressure points try massaging them with a spiky ball. You can get them from osteos or physios. Hang in there!