So day 8 after first chemo of TCH I felt extreme tiredness and shivery, temperature rose to 39.4 by time I got to emergency! ended up 4 nights in hospital on antibiotics as my white blood cells dropped to zero!! very scary. Had so many tests but no infection found, one of the doctors said just having no white blood cells could have caused very high temperature. Have to say I'm fed up as if I'd been given the nuelasta injection day after chemo could probably have avoided this happening, but when I asked for it was told to wait and see if I need it next time as it's expensive!!! well now ended up costing a lot more as ended up with hospital stay, injections, antibiotics, blood thinning injections!!!! Also a quick question, does anyone else have problems with having canula put in. omg what a nightmare, can only use left arm because of risk of lymphodema on right side. they had to get senior doctor to try using help of ultrasound and still couldn't get it in. Ended up with it on top of my foot! the pain was unbelievable. Apparently you are more sensitive to pain whilst on chemo, didn't know that.