I planned that I would go back to work once I'd settled into chemo but realised both physically and mentally I just couldn't do it. It was very hard for me to accept this and I was racked with guilt about it. But finally accepting it and taking the pressure off was a huge relief. I know of a number of women who could work and both in health industry and neither got sick because of it. It's really only that 1st cycle for most that is risky as after that most go on neulasta injections which will boost your immune system so you are less likely to get sick. I found the side effects on me were debilitating. But we all are different and as others have said you won't know until you start. Kath x