@CeeCee, I have had PICC line from my second AC infusion. I am close to the end of Taxol and they will remove it on the last day of chemo. I am so glad that I had PICC line, but I was not happy that they did not take my blood for test from the PICC line. Apparently, the Pathology team was not trained for that. One of the nurses from the Pathology team advised me to insist on having blood test from the cancer clinic where I was getting infusion. I asked and they agreed. Therefore, for the last 3 Taxol infusion and had a blood test a day before form the same place and will continue to the end. The insertion for PICC line was also painless.