I know it's late but if anyone could help me out I'd appreciate it. I'm going to bed but my ankle pain from Letrozole is the worst it's ever been. Panadol Osteo isn't working. I've got some drugs left over from the various operations I've had since last December. What would be the best to knock the pain on its head so I can sleep: a paracetemol & codeine combo, Tramadol, Oxycodone 5mg (aka Endone), Targin, and an anti-inflammatory diclofenac. Which would be best do you reckon? What's worked for you?