I had 12 rounds of paclitaxel and still have some residual effects of peripheral
neuropathy. That’s the bad news. Most people recover pretty quickly after treatment ends. Reactions vary really wildly so all you can do
is to be alert to symptoms and consider alternatives. Ice mitts and socks are recommended by some. Doses can be reduced if tingling in the extremities is experienced. I found vitamin B reduced the effects considerably. Some people don’t get any negative reactions at all. The good news? I am eleven years on with no evidence of disease. I agree with @Blossom1961 - the therapeutic dose is less than 12, so you may still get the same benefit with nine or ten. Why did I persevere? I discovered a lump under my right arm. It turned out to be entirely benign but settled what scared me most - my neuropathied feet or getting another cancer. I have no regrets and ultimately I think that’s important - to know you have done everything you reasonably can to not have cancer any more. Best wishes.