@Number2 I lost my hair everywhere between days 19-23. My scalp really hurt leading up to this so the second time around I shaved it off as soon as it started to hurt which made a huge difference. I didn’t lose my fingernails but lost a couple toenails. My nails were all chalky and ridged. Dark nail polish may reduce nail damage. Everyone reacts differently to the chemo so just be prepared for everything and hope you don’t need any of it. I do highly recommend antacids for the first night of chemo. My heartburn was horrendous and I was not prepared. Don’t be hesitant to ask your medical team for any drugs to alleviate symptoms. It is only for the short term and will help you stick the course. If you feel like venting, hop on this forum. We get it. Once again, any questions, ask away.