@Number2 We have the same type. Her2+ and ER/PR -. I had the neo adjuvant chemotherapy. Four doses three weeks apart followed by Paclitaxel every week for twelve weeks plus this is when the targeted therapy started. Herceptin every three weeks for a year. I had a mastectomy after the Paclitaxel treatment was complete. I did not have radio as it made no difference for me in regards to whether the cancer would return or not. I highly suggest you take them up if they offer you Perjeta with your Herceptin treatment. It reduces the chance of it returning. It will probably cost. My cancer is now metastatic and the perjeta may have prevented this. If you have any questions just ask. Sending big hugs