Hi @JenPritchard I have the same diagnosis as you, even the same 4.5cm lump. Also spread to my lymph nodes but body tests came back clear. Only had to remove part of my breast even though the tumor was large and got clear margins. Being hormone positive is a really good sign as my Dr said the Chemo is designed to work best with this type. I had a bad reaction to Chemo but that's just me and apparently rare so I'm sure you will tolerate it better. Please feel positive about the future as once the treatment has been completed, our type of cancer has a very high success rate for a cure. I hope you can lean on your husband for the days your not feeling so great but its important to remember (I just learnt this) that you feel better each day once that first week is over and almost back to normal half way through. It's very doable once you get over the fear of the unknown. Don't have children, so have to leave to others to advise on that. Lot of love and hugs coming your way. Be strong.