As the other ladies have said,Tamoxifen is not as bad for lots of us as we first thought .I have been on it for about 10 months now,and the only side effects are hot flushes( which I had before,and now they have almost disappeared)and leg cramps in bed,which magnesium has been great for.Give it a try,as a lot of these things have huge lists of side effects.( but so do all other medications too).It would depend on your individual circumstances as to when you would start Tamoxifen,but for me,I started 4 weeks after my last round of chemo.I didn't have radiotherapy.All the best and stay in touch.cheersxoxRobyn.