Hi @Estherch, this was how it was for me too and I struggled with not having as much energy as I normally did!! But I found getting out and walking each morning helped (sort of like I had achieved something as crazy as it sounds). I found the first week hard with nausea and fatigue but the two weeks following AC I was able to work part-time and resume normal household chores. I got into a cycle of what I could do and expect after the first session. I was taking three pramin a day with AC and chewing ginger to help with the nausea but thankfully when I started weekly paclitaxol the nausea went, I still feel fatigued but only three more treatments to go!! Be kind to yourself and take one day at a time