@Mkitty68 I found with Taxol, the pain hit about 48hrs later, and mine lasted a few days with the first infusion and then as they went I was in pain right up to the next infusion, it was relentless. Muscle, Nerve and bone pain all of it! I had the rash on both hands, nothing helped it so I just kept it moisturised. It stops when you finish, so that's good! Never heard anything about condoms through Chemo at all...this is the first Ive heard of it. I had FEC first time round, lost libido started to creep in and through taxol too...due to induced menopause 21 months later libido is still really low...all part of it so I'm told. Things change alot but have learnt to adapt. Hang in there xo Melinda