chemo generations

A bit more on the "generation" - @Zoffiel (Marg) hullo there, your analogy is brilliant - the big thing in chemo evolution is the introduction of the taxanes which are 3rd gen I think ... Anyway the thing is they can have "better" outcomes but only for certain varieties of the disease - nobody even knew these variants existed a few years ago- and the "cost" is often higher in terms of side effects. So you buy a new Holden which turns out to be a German engineered disguised Opel and it does great if you are in a big hurry on the Autobahn but it is horrible on gravel roads outside Yackandanda where the old Holden ute will be a lot more reliable and cost a lot less. For me using the various predict tools suggested a taxane would add a small percentage improvement in survival at a high cost in likely side effects because of existing comorbidities and my age. In the event I said no to chemo altogether and one onco I saw agreed that was a good decision providing I went on the Letrozole and stayed on it. But there are no guarantees and (all sing together) "Everyone is Different" . Thinking of you Becca you will get through this!